Publications

2020

60. Zhenghan Di#, Bei Liu#, Jian Zhao#, Zhanjun Gu, Yuliang Zhao*, Lele Li*. "An Orthogonally Regulatable DNA Nanodevice for Spatiotemporally Controlled Biorecognition and Tumor Treatment" Sci. Adv. 2020, 6, eaba9381. (#co-first author) [Link]

59. Yulei Shao, Bei Liu, Zhenghan Di, Ge Zhang, Ling-Dong Sun, Lele Li*, and Chun-Hua Yan. "Engineering of Upconverted Metal-Organic Frameworks for Near-Infrared Light-Triggered Combinational Photodynamic-/Chemo-/Immuno-Therapy Against Hypoxic Tumors" J. Am. Chem. Soc. 2020, 142, 3939-3946. [Link]

The article has been featured in Cover Paper.

58. Jian Zhao#, Yinghao Li#, Ming-Ming Yu, Zhanjun Gu, Lele Li*, and Yuliang Zhao. "Time-Resolved Activation of pH Sensing and Imaging in Vivo by Remotely Controllable DNA Nanomachine" Nano Lett. 2020, 20, 874-880. (#co-first author) [Link]

57. Chang Liu#, Bei Liu#, Jian Zhao#, Zhenghan Di, Daquan Chen, Zhanjun Gu, Lele Li*, and Yuliang Zhao*. "Nd3+‐Sensitized Upconversion Metal–Organic Frameworks for Mitochondria‐Targeted Amplified Photodynamic Therapy" Angew. Chem., Int. Ed. 2020, 59, 2634-2638. (#co-first author) [Link]

The article has been featured in Hot Paper.

56. Bei Liu#, Rui Ma#, Jian Zhao, Yuliang Zhao, and Lele Li*. "A smart DNA nanodevice for ATP-activatable bioimaging and photodynamic therapy" Sci. China Chem. 2020. (#co-first author) [Link]

55. Congli Wang, Zhenhan Di, Zetan Fan, and Lele Li*. "Self-assembly of DNA Nanostructures via Bioinspired Metal Ion Coordination" Chem. Res. Chinese U 2020, 36, 268–273. [Link] 

54. Junxiang Zhao, Chao Liu, Yike Li, Yao Ma, Jinqi Deng, Lele Li, and Jiashu Sun*. "Thermophoretic Detection of Exosomal microRNAs by Nanoflares" J. Am. Chem. Soc. 2020, 142, 4996-5001.  [Link]

53. Jiani Xie, Chengyan Wang, Ning Wang, Shuang Zhu, Linqiang Mei, Xiao Zhang, Yuan Yong, Lele Li, Chunying Chen, Changshui Huang*, Zhanjun Gu*, Yuliang Li, and Yuliang Zhao*. "Graphdiyne Nanoradioprotector with Efficient Free Radical Scavenging Ability for Mitigating Radiation-induced Gastrointestinal Tract Damage" Biomaterials, 2020, 244, 119940. [Link] 

52. Chengyan Wang, Jiani Xie, Xinghua Dong, Linqiang Mei, Maoru Zhao, Zhengwei Leng, Houxiang Hu, Lele Li, Zhanjun Gu*, and Yuliang Zhao. "Clinically Approved Carbon Nanoparticles with Oral Administration for Intestinal Radioprotection via Protecting the Small Intestinal Crypt Stem Cells and Maintaining the Balance of Intestinal Flora" Small 2020, 16, 1906915. [Link]

51. Xin Wang, Zhao Guo, Chenyang Zhang, Shuang Zhu, Lele Li, Zhanjun Gu*, and Yuliang Zhao. "Ultrasmall BiOI Quantum Dots with Efficient Renal Clearance for Enhanced Radiotherapy of Cancer" Adv. Sci. 2020, 7, 1902561. [Link]

50. Shuang Zhu, Lele Li, Zhanjun Gu*, Chunying Chen*, and Yuliang Zhao*. "15 Years of Small: Research Trends in Nanosafety" Small 2020, 2000980. [Link]

49. Deyao Zhao, Ge Yang, Qing Liu, Wenjing Liu, Yuhua Weng, Yi Zhao, Feng Qu, Lele Li, and Yuanyu Huang*. "A photo-triggerable aptamer nanoswitch for spatiotemporal controllable siRNA delivery" Nanoscale, 2020,12, 10939-10943. [Link]

2019

48. Hongqian Chu, Jian Zhao, Yongsheng Mi, Zhenghan Di, and Lele Li*, "NIR-Light-Mediated Spatially Selective Triggering of Anti-Tumor Immunity via Upconversion Nanoparticle-Based Immunodevices" Nat. Commun. 201910, 2839. [Link]

47. Hongqian Chu#, Jian Zhao#, Yongsheng Mi, Yuliang Zhao, and Lele Li*, "Near-infrared Light-Initiated Hybridization Chain Reaction for Spatially- and Temporally-Resolved Signal Amplification" Angew. Chem., Int. Ed. 2019, 10, 14877-14881.(#co-first author) [Link]

46. Zhenghan Di, Jian Zhao, Hongqian Chu, Wenting Xue, Yuliang Zhao, and Lele Li*, "An Acidic-Microenvironment-Driven DNA Nanomachine Enables Specific ATP Imaging in the Extracellular Milieu of Tumor" Adv. Mater. 2019, 31, 1901885. [Link]

Highlighted by MaterialsViewsChina

45. Bei Liu, Feng Hu, Jingfang Zhang, Congli Wang, and Lele Li*, "A Biomimetic Coordination Nanoplatform for Controlled Encapsulation and Delivery of Drug-Gene Combinations" Angew. Chem., Int. Ed. 2019, 58, 8804-8808. [Link]

Highlighted by ChemistryViews.org

44. Jian Zhao, Hongqian Chu, Ya Zhao, Yi Lu, and Lele Li*, "A NIR Light-Gated DNA Nanodevice for Spatiotemporally Controlled Imaging of MicroRNA in Cells and Animals" J. Am. Chem. Soc. 2019, 141, 7056-7062. [Link]

The article has been featured in Cover Paper.

43. Mengyuan Li#, Congli Wang#, Zhenghan Di#, Hui Li, Jingfang Zhang, Wenting Xue, Meiping Zhao, Ke Zhang, Yuliang Zhao, and Lele Li*,  "Engineering Multifunctional DNA Hybrid Nanospheres through Coordination-Driven Self-Assembly" Angew. Chem., Int. Ed. 2019, 58, 1350-1354. (#co-first author) [Link]

The article has been featured in Hot Paper.

42. Mengyuan Li, Jian Zhao, Hongqian Chu, Yongsheng Mi, Zehao Zhou, Zhenghan Di, Meiping Zhao, and Lele Li*, "Light-Activated Nanoprobes for Biosensing and Imaging" Adv. Mater. 2019, 31, 1804745. [Link]

 

41. Lele Li*, Hang Xing, Jingjing Zhang, Yi Lu*, "Functional DNA Molecules Enable Selective and Stimuli-Responsive Nanoparticles for Biomedical Applications" Acc. Chem. Res. 201952, 2415-2426. [Link]

40. Yongsheng Mi#, Hongbo Cheng#, Hongqian Chu, Jian Zhao, Mingming Yu, Zhanjun Gu, Yuliang Zhao*, and Lele Li*. "A Photochromic Upconversion Nanoarchitecture: towards Activatable Bioimaging and Dual NIR Light-programmed Singlet Oxygen Generation" Chem. Sci. 2019, 10, 10231-10239. (#co-first author) [Link]

The article has been featured in Cover Paper.

39. Bei Liu#, Jingfang Zhang#, and Lele Li*, "Metal-DNA Coordination-Driven Self-Assembly: A Conceptual Methodology to Expand the Repertoire of DNA Nanobiotechnology" Chem. Eur. J. 201925, 1-7. (#co-first author) [Link]

(Invited Concept Article)

38. Feng Hu#, Bei Liu#, Hongqian Chu, Chang Liu, Zhaohui Li, Daquan Chen*, and Lele Li*. "Real-time Monitoring of pH-responsive Drug Release Using a Metal-Phenolic Network-functionalized Upconversion Nanoconstruct" Nanoscale, 2019, 11, 9201–9206. (#co-first author) [Link]

37. Wenting Xue, Zhenghan Di, Ya Zhao, Aiping Zhang*, and Lele Li*. "DNA-mediated coordinative assembly of upconversion hetero-nanostructures for targeted dual-modality imaging of cancer cells" Chinese Chem. Lett. 2019, 30, 899–902. [Link]

2018

36. Zehao Zhou#, Mengyuan Li#, Jian Zhao, Zhenghan Di, Chunzhi Di, Bei Liu, Chao Zhang, Chun-Hua Yan and Lele Li*, "Trace Water Mediated Growth of Oriented Single-Crystalline Mesoporous Metal–Organic Frameworks on Gold Nanorods" Chem. Commun., 2018, 54, 8182-8185. (#co-first author) [Link]

The article has been featured in Back Cover Paper.

                             

35. Weiyu Ning#, Zhenghan Di#, Yingjie Yu#, Pingmei Zeng, Chunzhi Di, Daquan Chen,  Xueqian Kong, Guangjun Nie, Yuliang Zhao*, and Lele Li*, “Imparting Designer Biorecognition Functionality  to Metal–Organic Frameworks by a DNA-Mediated  Surface Engineering Strategy” Small  2018, 1703812. (#co-first author) [Link]

34. Jian Zhao#, Jinhong Gao#, Wenting Xue, Zhenghan Di, Hang Xing, Yi Lu, and Lele Li*, “Upconversion Luminescence-Activated DNA Nanodevice for ATP Sensing in Living Cells” J. Am. Chem. Soc. 2018140, 578-581. (#co-first author) [Link]

The article has been featured in Cover Paper, ACS Editors' ChoiceJACS spotlights and Nano Today (News and opinions)

2017

33. Yifan Li#, Zhenghan Di#, Jinhong Gao, Ping Cheng, Chunzhi Di, Ge Zhang, Bei Liu, Xinghua Shi, Ling-Dong Sun, Lele Li*, and Chun-Hua Yan, “Heterodimers Made of Upconversion Nanoparticles and Metal−Organic Frameworks” J. Am. Chem. Soc. 2017, 139, 13804-13810. (#co-first author) [Link]

 

Before 2016

32. Lele Li#, Rong Tong#, Mengyuan Li, Daniel S. Kohane*, “Self-assembled Gemcitabine-Gadolinium Nanoparticles for Magnetic Resonance Imaging and Cancer Therapy” Acta Biomater. 2016, 33, 34-39. (#co-first author) [Link]

31. Mengyuan Li, Lele Li, Changyou Zhan, Daniel S. Kohane*, “Core-Shell Nanostars for Multimodal Therapy and Imaging” Theranostics 2016, 6, 2306-2313. [Link]

30. LeLe Li, Yi Lu*, “Regiospecific Hetero-Assembly of DNA-Functionalized Plasmonic Upconversion Superstructures” J. Am. Chem. Soc. 2015137, 5272-5275. [Link]

29. Li Gao#, Le-Le Li#, Xiaolong Wang, Peiwen Wu, Yang Cao, Bo Liang, Xin Li, Yuanwei Lin, Yi Lu*, Xuefeng Guo*, “Graphene-DNAzyme Junctions: A Platform for Direct Metal Ion Detection with Ultrahigh Sensitivity” Chem. Sci. 20156, 2469-2473. (#co-first author) [Link]

28. Lele Li#, Rong Tong#, Hunghao Chu, Weiping Wang, Robert Langer*, Daniel S. Kohane*, “Aptamer Photoregulation In Vivo” Proc. Natl. Acad. Sci. U.S.A. 2014111, 17099-17103. (#co-first author) [Link]

27. Xiaoxia Hu, Ting Wei, Jie Wang, Zi-En Liu, Xinyang Li, Binhao Zhang, Zhihao Li, Lele Li*, Quan Yuan*, “Near-Infrared-Light Mediated Ratiometric Luminescent Sensor for Multimode Visualized Assays of Explosives” Anal. Chem. 201486, 10484-10491. [Link]

26. Le-Le Li, Peiwen Wu, Kevin Hwang, Yi Lu*, “An Exceptionally Simple Strategy for DNA-Functionalized Up-Conversion Nanoparticles as Biocompatible Agents for Nanoassembly, DNA Delivery, and Imaging” J. Am. Chem. Soc. 2013135, 2411–2414. [Link]

25. Le-Le Li#, Mengying Xie#, Jie Wang, Xinyang Li, Cheng Wang, Quan Yuan*, Dai-Wen Pang*, Yi Lu*, Weihong Tan, “A Vitamin-responsive Mesoporous Nanocarrier with DNA Aptamer-mediated Cell Targeting” Chem. Commun. 201349, 5823-5825. (#co-first author) [Link]

24. Le-Le Li, Ruobing Zhang, Leilei Yin, Kezhi Zheng, Weiping Qin, Paul R. Selvin, Yi Lu*, “Biomimetic Surface Engineering of Lanthanide-Doped Upconversion Nanoparticles as Versatile Bioprobes” Angew. Chem., Int. Ed. 201251, 6121-6125. [Link]

23. Le-Le Li#, Qian Yin#, Jianjun Cheng, Yi Lu*, “Polyvalent Mesoporous Silica Nanoparticle-Aptamer Bioconjugates Target Breast Cancer Cells” Adv. Healthcare Mater. 20121, 567-572. (#co-first author) [Link]

22. Le-Le Li, Pinghua Ge, Paul R. Selvin, Yi Lu*, “Direct Detection of Adenosine in Undiluted Serum Using a Luminescent Aptamer Sensor Attached to a Terbium Complex” Anal. Chem. 201284, 7852-7856. [Link]

21. Rui Guo, Le-Le Li, Wen-Hua Zhao, Yu-Xi Chen, Xiao-Zhu Wang, Chen-Jie Fang*, Wei Feng, Tian-Lan Zhang, Xiang Ma, Meng Lu, Shi-Qi Peng*, Chun-Hua Yan, “The Intracellular Controlled Release from Bioresponsive Mesoporous Silica with Folate as both Targeting and Capping Agent” Nanoscale 20124, 3577-3583. [Link]

20. Rui Guo, Le-Le Li, Hua Yanga, Mei-Jin Zhang, Chen-Jie Fang, Tian-Lan Zhang, Yi-Bing Zhang, Guo-Hui Cui, Shi-Qi Peng, Wei Feng, Chun-Hua Yan*, “Tuning Kinetics of Controlled-Release in Disulfide-Linked MSN-Folate Conjugates with Different Fabrication Procedures” Mater. Lett. 201266, 79-82. [Link]

19. Zhen-Xing Li, Fu-Bo Shi, Le-Le Li, Tao Zhang, Chun-Hua Yan*, “A Facile Route to Ordered Mesoporous-Alumina-Supported Catalysts, and their Catalytic Activities for CO Oxidation” Phys. Chem. Chem. Phys. 201113, 2488-2491. [Link]

18. Le-Le Li, Xue-Feng Fu, Zhen Ren, Ya-Guang Zhao, Wei Feng, Chun-Hua Yan*, “Hierarchical Self-Assembly of Superlattice Hybrids Consisting of Periodic and Alternating Cores of Porphyrin Molecules Separated by Nanoscale Silica Walls” Langmuir 2010, 26, 15730–15733. [Link]

17. Quan Yuan, Hao-Hong Duan, Le-Le Li, Zhen-Xing Li, Wen-Tao Duan, Le-Sheng Zhang, Wei-Guo Song, Chun-Hua Yan*, “Homogeneous Dispersed Ceria Nanocatalyst Stabilized with Ordered Mesoporous Alumina” Adv. Mater. 201022, 1475–1478. [Link]

16. Cheng Chen, Ling-Dong Sun, Zhen-Xing Li, Le-Le Li, Jun Zhang, Chun-Hua Yan*, “Ionic-Liquid-Based Route to Spherical NaYF4 Nanoclusters with the Assistance of Microwave Radiation and Their Multicolor Upconversion Luminescence” Langmuir 2010, 26, 8797–8803. [Link]

15. Le-Le Li, Hao Sun, Yan-Chun Bai, Chen-Jie Fang, Chun-Hua Yan*, “Orientational Organization of Organic Semiconductors within Periodic Nanoscale Silica Channels: Modification of Fluorophore Photophysics through Hierarchical Self-Assembly” Chem. Eur. J. 200915, 4716-4724. [Link]

14. Le-Le Li, Jun Xu, Quan Yuan, Zhen-Xing Li, Wei-Guo Song, Chun-Hua Yan*, “Facile Synthesis of Macrocellular Mesoporous Foam-like Ce-Sn Mixed Oxide with Nanocrystalline Frameworks by Using Triblock Copolymer as Single-Template” Small 20095, 2730-2737. [Link]

13. Le-Le Li, Hao Sun, Chen-Jie Fang, Quan Yuan, Ling-Dong Sun, Chun-Hua Yan*, “Mesostructured Hybrids Containing Potential Donors and Acceptors with Molecular-scale and Meso-scale Segregation and Ordering: Toward the Development of Smart Materials through Hierarchical Self-assembly” Chem. Mater. 200921, 4589-4597. [Link]

12. Le-Le Li, Wen-Tao Duan, Quan Yuan, Zhen-Xing Li, Hao-Hong Duan, Chun-Hua Yan*, “Hierarchical g-Al2O3 Monoliths with Highly Ordered 2D Hexagonal Mesopores in Macroporous Walls” Chem. Commun. 2009, 6174-6176. [Link]

11. Le-Le Li, Ling-dong Sun, Ya-Wen Zhang, Chun-Hua Yan*, “Functional-Template Directed Self-Assembly (FTDSA) of Mesostructured Organic–Inorganic Hybrid Materials” Sci. China Ser. B 200952, 1759-1768. [Link]

10. Quan Yuan, Le-Le Li, Shu-Liang Lu, Hao-Hong Duan, Zhen-Xing Li, Yue-Xiang Zhu, Chun-Hua Yan*, “General and Facile Synthesis of Zr-based Functional Materials with Highly Ordered Mesoporous Structures” J. Phys. Chem. C 2009113, 4117-4124. [Link]

9. Zhen-Xing Li, Le-Le Li, Huan-Ping Zhou, Quan Yuan, Cheng Chen, Ling-Dong Sun, Chun-Hua Yan*, “Colour Modification Action of an Upconversion Photonic Crystal” Chem. Commun. 2009, 6616-6618. [Link]

8. Quan Yuan, Yang Liu, Le-Le Li, Zhen-Xing Li, Chen-Jie Fang, Wen-Tao Duan, Xing-Guo Li, Chun-Hua Yan*, “Highly Ordered Mesoporous Titania-Zirconia Photocatalyst for Applications in Water Splitting and Degradation of Rhodamine-B” Micropor. Mesopor. Mater2009124, 169-178. [Link]

7. Quan Yuan, Hao-Hong Duan, Le-Le Li, Ling-Dong Sun, Ya-Wen Zhang, Chun-Hua Yan*, “Controlled Synthesis and Assembly of Ceria-based Nanomaterials” J. Collloid Interf. Sci. 2009, 335, 151-167. [Link]

6. Xiao-Fei Fu, Yan-Feng Yue, Rui Guo, Le-Le Li, Wei Sun, Chen-Jie Fang*, Chun-Hu Xu, Chun-Hua Yan*, “An Enhanced Fluorescence in a Tunable Face-to-Face p-p Stacking Assembly Directed by the H-Bonding” Cryst Eng Comm 2009, 11, 2268-2271. [Link]

5. Le-Le Li, Chen-Jie Fang, Hao Sun, Chun-Hua Yan*, “Hierarchical Self-assembly of pH-Responsive Nanocomposites with Molecular-scale and Mesoscale Periodicities” Chem. Mater. 200820, 5977-5986. [Link]

4. Le-Le Li, Wei-Ming Zhang, Quan Yuan, Zhen-Xing Li, Chen-Jie Fang, Ling-Dong Sun, Li-Jun Wan, Chun-Hua Yan*, “Room Temperature Ionic Liquids Assisted Green Synthesis of Nanocrystalline Porous SnO2 and Their Gas Sensor Behaviors” Cryst. Growth Des. 20088, 4165-4172. [Link]

3. Zhen-Xing Li, Le-Le Li, Quan Yuan, Wei Feng, Jun Xu, Ling-Dong Sun, Wei-Guo Song, Chun-Hua Yan*, “Sustainable and Facile Route to Nearly Monodisperse Spherical Aggregates of CeO2 Nanocrystals with Ionic Liquids and Their Catalytic Activities for CO Oxidation” J. Phys. Chem. C 2008112, 18405-18411. [Link]

2. Le-Le Li, Chen-Jie Fang, Quan Yuan, Chun-Hua Yan*, “Stabilization of Facial Isomer of Tris(8-hydroxyquinolinate) Aluminum though Confinement in Silica-Surfactant Mesostructures” Appl. Phys. Lett. 200790, 231908. [Link]

1. Le-Le Li, Hao Sun, Chen-Jie Fang, Jun Xu, Jing-Yi Jin, Chun-Hua Yan*, “Optical Sensors Based on Functionalized Mesoporous Silica SBA-15 for the Detection of Multianalytes (H+, Cu2+) in Water” J. Mater. Chem. 200717, 4492–4498. [Link]